837 From genotoxic stresses to skin damage: Distinct, novel mechanisms of skin and hair damage in chemo/radiation therapy
نویسندگان
چکیده
منابع مشابه
Melatonin Role in Ameliorating Radiation-induced Skin Damage: From Theory to Practice (A Review of Literature)
Normal skin is composed of epidermis and dermis. Skin is susceptible to radiation damage because it is a continuously renewing organ containing rapidly proliferating mature cells. Radiation burn is a damage to the skin or other biological tissues caused by exposure to radiofrequency energy or ionizing radiation. Acute skin reaction is the most frequently occurring side effect of radiation thera...
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مراقبت از پوست نوزادانی که با وزن کمتر از ۲۵۰۰ گرم متولد می شوند، در ۲۱ روز اول پس از تولد یکی از وظایف مهم پرستاری می باشد. گرچه در یک آمارگیری در آمریکا تعداد نوزادان با وزن کمتر از ۲۵۰۰ گرم حدود ۱-۰/ ۶٪ گزارش شده است، اما جهت افزایش شانس زنده ماندن آنها و هم چنین پیشگیری از بروز عفونت مسئله مراقبت از پوست اهمیت می یابد. در گذشته بیشتر نوزادان نارس بعلت سپتی سمی و یا عدم تعادل آب و الکترولیت ...
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Epidemiological studies suggest a correlation between increased airborne particulate matter (PM) and adverse health effects. The mechanisms of PM-health effects are believed to involve oxidative stress and inflammation. To evaluate the ability of PM promoting skin tissue damage, one of the main organs exposed to outdoor pollutants, we analyzed the effect of concentrated ambient particles (CAPs)...
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Solar radiation induces acute and chronic reactions in human and animal skin. Chronic repeated exposures are the primary cause of benign and malignant skin tumors, including malignant melanoma. Among types of solar radiation, ultraviolet B (290-320 nm) radiation is highly mutagenic and carcinogenic in animal experiments compared to ultraviolet A (320-400 nm) radiation. Epidemiological studies s...
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The concept of systemic photoprotection by dietary means is gaining momentum. Skin is continuously exposed to ultraviolet (UV) radiation, the major cause of skin disorders such as sunburn, photodamage, and nonmelanoma skin cancer. Most of the erythemal annual UV dose is encountered under nonvacation conditions, when no sunscreen is applied. In the absence of topically added compounds, skin prot...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.02.863